Free delivery on orders over 40€ in mainland France

  • DUOLYS.A Retinol Serum  - 2
  • DUOLYS.A Retinol Serum  - 3
  • The multi-action anti-ageing serum
The multi-action anti-ageing serum

Nos kits Duolys

DUOLYS.A Retinol Serum

Multi-actions, this serum with 10 ingredients only and a silky texture acts on all the skin ageing.  For people over the age of 30 years.

Intensive anti-wrinkles serum

Ideal for:

All skin types : 30 years old and +


Oil-serum, Light, Non-sticky


Once a day, preferably in the evening

Improve the appearance of the signs of ageing , refines the skin texture, smooths wrinkles, attenuates skin blemishes

30 ml glass bottle + pipette

Ou trouver le produit ?

Free delivery
starting at 60€ purchase in Europe

Need help? 01 73 00 58 515d/7 by email

*GERSDATA - Prescription hair and nail food supplements market in France in value, 2023

Multi-actions, this serum with 10 ingredients only and a silky texture acts on all the skin ageing.  For people over the age of 30 years.

Turning back the signs of ageing thanks to the multi-action anti-ageing serum Duolys A. Containing only 10 ingredients, and with its unique and synergistic combination of Retinol and Tocopheryl retinoate, DUOLYS.A improves all the signs of ageing : wrinkles, lines, blemishes and skin texture, without ever irritating the skin and protecting it from the damage caused by oxidative stress.

Its exceptional galenic formula with its “oil-serum” texture is immediately absorbed into the skin with no sticky finish. Its ultra-light texture leaves skin feeling silky and velvety-soft. Your anti-ageing beauty routine is transformed into a moment of pure pleasure.

Day after day, skin appears firmer and complexion is more radiant Skin texture is refined. Wrinkles are less visible and skin imperfections are reduced.

98% ingredients of natural origin

Face – Neck – Neckline


Light and non-sticky “oil-serum” texture

Silky, soft and non-greasy finish

Non-comedogenic, non-acnegenic – No fragrance

37 Items

Data sheet

Skin type
All skin types
Prone to brown spots
Dullness, dark circles
Wrinkles, firmness
Skincare type

Anti-ageing efficacy proven in studies

Over 90% of women would like to continue using the product (1,b)

Very good skin tolerance


1.Evaluation of the cutaneous acceptability and comedogenic potential of Duolys.A, conducted under dermatological control on 22 adult women over 28 days aged between 20 and 47 years old

a.       Tolerance 

No clinical signs of intolerance were observed and no functional or physical signs were reported by volunteers at D28.

The product demonstrates very good skin tolerance.

b.      Patient evaluation

Users responded very positively to Duolys.A: over 90% of women would like to continue using the product.

-          100%* find the texture pleasant and non-sticky with a silky finish

-          100%* say their skin is smoother

-          100%* have softer, deeply-moisturised skin

-          95%* find that skin texture is refined

-          82%* say skin appears younger

-          87%* find that the product reduces skin imperfections

-          85%* : Rides moins visibles (constaté sur 13 volontaires)

*% of satisfaction

2. Anti-ageing efficacy proven in studies on human (ex vivo)

  • Significant increase (20 to 30%) in collagen i from day 4 and iii synthesis in the dermis from day 9
  • 10% significant increase in epidermal thickness from day
  • Excellent skin tolerance - In contrast to the results usually obtained with vitamin A-based products (retinol, retinaldehyde, retinoic acid), which generally cause inflammation and a decrease in cell viability, Duolys.A Intensive Anti-Wrinkle Serum offers optimal skin tolerance and does not affect cell viability.

A combination of Retinol and Tocopheryl retinoate with optimal tolerance

Minimalist formula with just 10 essential ingredients

Caprylic/Capric Triglyceride, Hydrogenated Coconut Acid, Dicaprylyl Carbonate, Coco-Caprylate/Caprate, Castor Oil/IPDI Copolymer, Retinol, Tocopherol, Tocopheryl Retinoate, Helianthus Annuus (Sunflower) Seed Oil, Glycine Soja (Soybean) Oil

Proven results







Tips and tricks

Apply a small amount of Duolys.A to the face, neck and neckline, preferably in the evening, to previously cleansed skin.

Avoid contact with eyes. For optimal results, use as a 3-month repeatable treatment. It can also be used in combination with Duolys.CE or as a follow-up treatment for cosmetic procedures.

If you experience a tingling sensation, apply less frequently. Not for use by pregnant women or those planning a pregnancy. Limit sun exposure and apply an appropriate sun protective product. Keep the product at a temperature below 25°C.

Frequently asked questions

All ACM care products are available in pharmacies and para-pharmacies. Unfortunately, not all pharmacies stock our products. However, they can be ordered from our laboratory, or from pharmaceutical wholesalers..

Cosmetics regulations have banned testing the efficacy and safety of cosmetic products on animals since 2004. ACM, being a responsible manufacturer, complies with the provisions of European Regulation 1223/2009 on cosmetic products and its amendments, and in particular with article 18 concerning animal testing. We can confirm that our cosmetic products have not been tested on animals.

Our formulas have proven stability of over thirty months. You can trust the expiry date displayed on their packaging. Until that date, we guarantee the effectiveness and stability of our formulas.

The Period After Opening (PAO), generally varies from six to twenty-four months. It is displayed on the packaging of all our products, in the form of a symbol representing an open jar of cream with a number and the letter “M”, expressed in months. The figure is the number of months during which the product can be used risk-free after opening.

Our face care products have been tested to show that they are noncomedogenic, meaning that they do not promote the appearance of comedones and do not clog pores. You can find the label “noncomedogenic” displayed on our packaging.

Customer reviews

Additional products